Generally speaking.....the Holy Spirit does not lead us to gather in large buildings ....this started happening several hundred years after Christ rose from the dead, when Christianity became the official "religion" of the land. Satan's strategy was (and is)  - if you can't beat em', join em'. Prior to that time the believers met house to house, where the Holy Spirit was welcomed and where His will was done. Large buildings became an excellent way for Satan (through men) to control and influence large amounts of people. One reason is because people are more comfortable in crowds - they can remain anonymous and they feel if large numbers of people are accepting it - it must be ok. In a house setting,  we are much more likely to be exposed to intimacy  - with God and with each other. And it's harder for a man to replace the Holy Spirit in the lives of the people (Satan's goal) in a house setting.  False doctrines and demonic spirits can be much more easily exposed and confronted....

Having said all this  - God did sanction and call the people to gather together in "solemn assemblies" - feasts  - some somber, others joyous celebrations - so, it would be a good thing for saints to meet together in large numbers seven times a year, in my opinion.